A 59-year-old presented with an area of midperipheral pigmentation. What is this lesion?

Analysis
This is a scan of the peripheral retina. This is why the retina is thin (as opposed to the macular scans which we typically see). If one looks closely, the nerve fiber layer (NFL), inner nuclear layer (INL) and outer nuclear layer (ONL) are all visible. The RPE is visible (A). Just beneath and anterior to the RPE there is an intense area of hyperreflectivity. This is associated with a deeper shadow. This lesion is consistent with a hemorrhage beneath the RPE.
The patient was diagnosed with a peripheral choroidal neovascular membrane secondary to histoplasmosis.

OCT Tip
Deep hyperreflectivity represents hemorrhage until proven otherwise.
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