OCT Academy

OCT Mastery - Tip of the week

238. Hyporeflective Cysts in the Inner Retina

Sanjay Sharma
Sanjay Sharma
MD, MSc (Epid), MBA
Professor of Ophthalmology, Queen's University

OCT Tip 238 was originally published on July 22th, 2022.

This 64-year-old has blurred vision. Why?

Tip #237


In this image there are significant areas of pockets of hyporeflectivity in the retina consistent with cystoid macular edema. There is also the presence of a hyperreflective lesion in the inner retina, consistent with a micro aneurysm. The patient was known to have a history of malignant melanoma treated with plaque radiotherapy (video).

The patient was diagnosed with radiation retinopathy.

In this tip's accompanying 11 min. video, we'll review:

  • Causes of cystoid macular edema
  • Presentation of radiation retinopathy
  • Reinforce when to think/ask about a history of radiation
Tip #237 Analysis


In a patient with cystoid macular edema, always consider the possibility of radiation retinopathy.

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